Nuqui is directly located at the pacific coast, a region that is hard to reach from other parts of the country. Only Bahia Solano, further north, has an airport, too. Backpackers and locals told me that there are cargo ships going from Buenaventura, passing Nuqui 2 days after. Apart from that one could take a motorboat from Quibdó through the deep amazon forest to reach the coast.
Travellers come to Nuqui because of the beauty and pristine nature of its neighbouring villages. The communities here are living close to nature, earning their income with fishing and eco-, and community based toursim. There are fantastic opportunities to get a taste on the freshest sea food and fish. Activities mostly involve forest walks, birdwatching and foremost whale watching. In a small motorboat the go out into deep water along the coast and look out for the big beauties. Locals have stunning knowledge about the giants of the seas. Make sure you visit the Chocó in whale season as watchting them as they train their kids for hunting is a moving experience.
Once arrived at the small airport (normally in early afternoon) you can take the public boat from the harbour, if it is running on that exact day. The huge network of rivers is the only way to get imported goods into the area and unloading a boat definitively looks like pure manpower. Apart from that, the Chocó is a slow region, it feels almost like a different world.
In case you missed that public boat you can ask locals. Many have motorized boats as well and offer private charters. The fuel nevertheless is much more expensive as in the rest of Colombia, so that you have to calculate with some extra money.
Everything bears its cost. Take enough cash with you. There are no cash machines, but a dodgy outpost of a big colombian bank that only serves customers with colombian credit cards.
Any situation can be intense for itself. Accept to trade-off, to really enjoy the paradise. The transport is of course part of the adventure.